A team at MIT has developed a wearable sensor that predicts cold urticaria flare-ups before they occur, offering users a chance to take preventive action. The device, called ThermoGuard, sticks to the skin like a patch and continuously monitors local temperature, humidity, and mast cell activity via biomarkers in sweat.
Using AI algorithms, ThermoGuard analyzes these data points to predict when a reaction is imminent. If the risk is high, it vibrates and sends an alert to the user’s smartphone, prompting them to move to a warmer environment or take medication. Early trials showed an 89% accuracy rate in predicting reactions within a 10-minute window.
The device is particularly promising for children, who may not recognize early symptoms. Parents can receive real-time alerts and track their child’s triggers over time. The MIT team plans to launch a consumer version by late 2025, pending FDA approval.
Meanwhile, researchers are exploring broader applications, such as integrating ThermoGuard with smart home systems to automatically adjust room temperatures when a reaction is likely. This innovation marks a significant leap forward in managing cold allergy, transforming it from a reactive to a proactive condition.
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